On one of my two Macs (a 2012 i5 iMac running 10.14.6), Studio One 5.01 hangs while scanning VST 2.4 plugins. It does this even if I get rid of the two stock folders in Preferences, add a new folder, and put any VST (or none!) in it. On my other Mac, a 2018 Mac mini running Catalina, I have no issues at startup. I thought it was a particular plugin causing the issue, but as noted, it happens with ANY plugin, or even with NO plugins, in the folder set in Preferences.