Having the exact same issue on my Macbook Pro with Catalina.. I thought I was going crazy but it seems to be an issue if someone else is having it.
When I'm in Studio One...
When I switch to another app..
When I'm in a session and moving between Google Chrome or YouTube, this can create delays of 5-10 seconds with the spinning beach ball before I get control back. This can be problematic if I'm listen to some other music or a reference track in another application.