I have not yet upgraded, because the latest fix for 4.6 already didn't work out for me.
But allow me to say this:
Dear Presonus, as we have faith in your product, please have faith in your customers
when they say: There are several things that have stopped working in version 5!
It's in the code. I'm sure it is. Even a genius makes mistakes sometimes. It's just natural.
Every programer knows better than me: A single typo bug can mess up things.